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GolgiCell

sc_neurocore_engine::neurons::cerebellar

Struct GolgiCell 

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pub struct GolgiCell {
Show 36 fields
    pub v: f64,
    pub m: f64,
    pub h: f64,
    pub p_na: f64,
    pub n: f64,
    pub a: f64,
    pub b: f64,
    pub w: f64,
    pub m_t: f64,
    pub s: f64,
    pub c_n: f64,
    pub r: f64,
    pub ca: f64,
    pub g_na_t: f64,
    pub g_na_p: f64,
    pub g_kdr: f64,
    pub g_ka: f64,
    pub g_km: f64,
    pub g_cat: f64,
    pub g_can: f64,
    pub g_bk: f64,
    pub g_sk: f64,
    pub g_h: f64,
    pub g_l: f64,
    pub e_na: f64,
    pub e_k: f64,
    pub e_ca: f64,
    pub e_h: f64,
    pub e_l: f64,
    pub c_m: f64,
    pub tau_ca: f64,
    pub kd_bk: f64,
    pub kd_sk: f64,
    pub dt: f64,
    pub sub_steps: usize,
    pub gain: f64,

}
Expand description

Cerebellar Golgi cell — Solinas et al. 2007 full model.

Large inhibitory interneuron in the granular layer. Provides tonic and phasic GABAergic/glycinergic inhibition to granule cells. Spontaneously active at 3-10 Hz due to intrinsic pacemaker currents.

Full Solinas 2007 model with 11 ionic currents:

  • INa_t (transient Na, m³h): fast spike generation
  • INa_p (persistent Na, p): subthreshold oscillations, pacemaking
  • IK_dr (delayed rectifier K, n⁴): repolarisation
  • IK_A (A-type K, a³b): onset delay, inter-spike interval
  • IK_M (muscarinic/slow K, w): spike frequency adaptation
  • ICa_T (T-type Ca²⁺, m_t²s): rebound, subthreshold oscillations
  • ICa_N (N-type Ca²⁺, c²): high-voltage activated, AHP trigger
  • IBK (BK, Ca²⁺+V dependent): fast AHP
  • ISK (SK, Ca²⁺ dependent): slow AHP, pacemaker regulation
  • Ih (HCN, r): sag, resting potential, pacemaker contribution
  • IL (leak)

10 sub-steps (dt_sub = 0.05 ms) for Na gating stability.

Solinas et al., Front Cell Neurosci 1:2, 2007.

Fields§

§v: f64§m: f64§h: f64§p_na: f64§n: f64§a: f64§b: f64§w: f64§m_t: f64§s: f64§c_n: f64§r: f64§ca: f64§g_na_t: f64§g_na_p: f64§g_kdr: f64§g_ka: f64§g_km: f64§g_cat: f64§g_can: f64§g_bk: f64§g_sk: f64§g_h: f64§g_l: f64§e_na: f64§e_k: f64§e_ca: f64§e_h: f64§e_l: f64§c_m: f64§tau_ca: f64§kd_bk: f64§kd_sk: f64§dt: f64§sub_steps: usize§gain: f64

Implementations§

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impl GolgiCell

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pub fn new() -> Self

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fn boltz(v: f64, vh: f64, k: f64) -> f64

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pub fn step(&mut self, current: f64) -> i32

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pub fn reset(&mut self)

Trait Implementations§

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impl Clone for GolgiCell

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fn clone(&self) -> GolgiCell

Returns a duplicate of the value. Read more
1.0.0 (const: unstable) · Source§

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for GolgiCell

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for GolgiCell

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fn default() -> Self

Returns the “default value” for a type. Read more

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fn borrow_mut(&mut self) -> &mut T

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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
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