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GranuleCell

sc_neurocore_engine::neurons::cerebellar

Struct GranuleCell 

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pub struct GranuleCell {
Show 30 fields
    pub v: f64,
    pub m: f64,
    pub h: f64,
    pub n: f64,
    pub a: f64,
    pub b: f64,
    pub m_t: f64,
    pub s: f64,
    pub ca: f64,
    pub r: f64,
    pub c_m: f64,
    pub g_na: f64,
    pub g_kdr: f64,
    pub g_ka: f64,
    pub g_t: f64,
    pub g_kca: f64,
    pub g_h: f64,
    pub g_l: f64,
    pub g_tonic: f64,
    pub e_na: f64,
    pub e_k: f64,
    pub e_ca: f64,
    pub e_h: f64,
    pub e_l: f64,
    pub e_gaba: f64,
    pub tau_ca: f64,
    pub kd_kca: f64,
    pub dt: f64,
    pub sub_steps: usize,
    pub gain: f64,

}
Expand description

Cerebellar granule cell — D’Angelo et al. 2001 full model.

Most numerous neuron in the brain (~50%). Tiny soma (6-8 µm), four short dendrites receiving mossy fibre input at glomeruli, output via parallel fibres to Purkinje cells.

Full Hodgkin-Huxley-type model with 7 ionic currents:

  • INa (transient Na, m³h): fast spike generation
  • IK_dr (delayed rectifier K, n⁴): repolarisation
  • IK_A (A-type K, a³b): delay to first spike, inter-spike interval
  • ICa_T (T-type Ca²⁺, m_t²s): post-inhibitory rebound bursting
  • IK_Ca (Ca²⁺-activated K, Hill): slow AHP
  • Ih (HCN, r): sag current, resting potential stabilisation
  • IL (leak)
  • IGABA (tonic GABA from Golgi cells)

Uses 4 sub-steps (dt_sub = 0.125 ms) for Na gating stability.

D’Angelo et al., J Neurosci 21(3):759, 2001. D’Angelo & De Zeeuw, Trends Neurosci 32:30, 2009 (review).

Fields§

§v: f64§m: f64§h: f64§n: f64§a: f64§b: f64§m_t: f64§s: f64§ca: f64§r: f64§c_m: f64§g_na: f64§g_kdr: f64§g_ka: f64§g_t: f64§g_kca: f64§g_h: f64§g_l: f64§g_tonic: f64§e_na: f64§e_k: f64§e_ca: f64§e_h: f64§e_l: f64§e_gaba: f64§tau_ca: f64§kd_kca: f64§dt: f64§sub_steps: usize§gain: f64

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impl GranuleCell

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pub fn new() -> Self

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fn boltz(v: f64, vh: f64, k: f64) -> f64

Boltzmann steady-state.

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pub fn step(&mut self, current: f64) -> i32

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pub fn reset(&mut self)

Trait Implementations§

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impl Clone for GranuleCell

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fn clone(&self) -> GranuleCell

Returns a duplicate of the value. Read more
1.0.0 (const: unstable) · Source§

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for GranuleCell

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for GranuleCell

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fn default() -> Self

Returns the “default value” for a type. Read more

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impl<T> Any for T
where T: 'static + ?Sized,

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fn type_id(&self) -> TypeId

Gets the TypeId of self. Read more
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impl<T> Borrow<T> for T
where T: ?Sized,

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fn borrow(&self) -> &T

Immutably borrows from an owned value. Read more
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impl<T> BorrowMut<T> for T
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fn borrow_mut(&mut self) -> &mut T

Mutably borrows from an owned value. Read more
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impl<T> CloneToUninit for T
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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
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impl<T> From<T> for T

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fn from(t: T) -> T

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fn into(self) -> U

Calls U::from(self).

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fn into_either_with<F>(self, into_left: F) -> Either<Self, Self>
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impl<T> Pointable for T

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const ALIGN: usize

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type Init = T

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unsafe fn init(init: <T as Pointable>::Init) -> usize

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unsafe fn drop(ptr: usize)

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type Owned = T

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fn vzip(self) -> V

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