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GapJunctionNeuron

sc_neurocore_engine::neurons::misc

Struct GapJunctionNeuron 

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pub struct GapJunctionNeuron {
Show 15 fields
    pub v: f64,
    pub c_m: f64,
    pub g_l: f64,
    pub e_l: f64,
    pub g_gap: f64,
    pub i_tonic: f64,
    pub v_threshold: f64,
    pub v_reset: f64,
    pub refractory: f64,
    pub refrac_timer: f64,
    pub rect_v0: f64,
    pub rect_a: f64,
    pub rect_gmin: f64,
    pub dt: f64,
    pub gain: f64,

}
Expand description

Neuron with electrical synapse (gap junction) coupling.

Models neurons coupled via connexin-based gap junctions that allow direct electrical current flow between cells. Found extensively in:

  • Inferior olive neurons (climbing fibre system)
  • Retinal ganglion cells (coupled networks)
  • Cortical interneuron networks (PV+ basket cell syncytia)
  • Thalamic reticular nucleus

Includes voltage-dependent rectification (Cx36 gating): g_eff = g_gap * g_inf(V_j) g_inf = g_min + (1 - g_min) / (1 + exp(A * (|V_j| - V_0)))

where V_j = V_neighbor - V is the transjunctional voltage, g_min is the residual conductance at large V_j, V_0 is the half-inactivation voltage (~30 mV for Cx36), and A is the voltage sensitivity (~0.1 mV⁻¹).

At small |V_j| < V_0: near-full conductance (bidirectional). At large |V_j| > V_0: conductance drops to g_min (rectification).

C dV/dt = -g_L(V - E_L) + g_eff * (V_neighbor - V) + I_tonic

Connors & Long, Annu Rev Neurosci 27:393, 2004. Vervaeke et al., Neuron 65:801, 2010 (Cx36 voltage gating).

Fields§

§v: f64§c_m: f64§g_l: f64§e_l: f64§g_gap: f64§i_tonic: f64§v_threshold: f64§v_reset: f64§refractory: f64§refrac_timer: f64§rect_v0: f64§rect_a: f64§rect_gmin: f64§dt: f64§gain: f64

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impl GapJunctionNeuron

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pub fn new() -> Self

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fn rect_conductance(&self, v_j: f64) -> f64

Voltage-dependent gap junction conductance (Cx36 gating).

g_inf = g_min + (1 - g_min) / (1 + exp(A * (|V_j| - V_0)))

Symmetric in |V_j|: rectification acts for both polarities.

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pub fn step(&mut self, current: f64) -> i32

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pub fn reset(&mut self)

Trait Implementations§

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impl Clone for GapJunctionNeuron

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fn clone(&self) -> GapJunctionNeuron

Returns a duplicate of the value. Read more
1.0.0 (const: unstable) · Source§

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for GapJunctionNeuron

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for GapJunctionNeuron

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fn default() -> Self

Returns the “default value” for a type. Read more

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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
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