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InnerHairCell

sc_neurocore_engine::neurons::sensory

Struct InnerHairCell 

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pub struct InnerHairCell {
Show 22 fields
    pub v: f64,
    pub v_rest: f64,
    pub tau: f64,
    pub g_met: f64,
    pub x_half: f64,
    pub s_met: f64,
    pub ca: f64,
    pub tau_ca: f64,
    pub g_ca: f64,
    pub v_ca_half: f64,
    pub s_ca: f64,
    pub q: f64,
    pub c: f64,
    pub w: f64,
    pub m_pool: f64,
    pub y: f64,
    pub x_r: f64,
    pub k_rel: f64,
    pub l: f64,
    pub r_up: f64,
    pub k_d: f64,
    pub dt: f64,

}
Expand description

Inner hair cell — primary auditory transducer.

Mechano-electrical transduction: stereocilia displacement opens MET channels → depolarisation → Ca2+ influx → glutamate release. Inner hair cell with Meddis vesicle pool dynamics.

Three-stage model per Meddis (1986, 2006):

  1. MET transduction: Boltzmann gating of mechano-electrical transducer channels converts stereocilia displacement to receptor potential.

  2. Ca²⁺ dynamics: voltage-dependent Ca²⁺ entry drives vesicle release.

  3. Meddis vesicle pool: three-compartment transmitter model:

    • q: available vesicles (free pool)
    • c: cleft transmitter concentration
    • w: reprocessing store (depleted vesicles recovering)

    dq/dt = y*(M-q) + x_rw - kqf(Ca) (replenishment + recovery - release) dc/dt = kqf(Ca) - lc - r_upc (release - loss - reuptake) dw/dt = r_upc - x_r*w (reuptake - recovery)

    where f(Ca) = Ca²/(Ca² + K_d²) is Ca²⁺-dependent release rate.

Graded output: receptor potential (no spikes).

Meddis, JASA 79:702, 1986. Meddis, JASA 119:406, 2006. Lopez-Poveda & Eustaquio-Martín, JASA 119:416, 2006.

Fields§

§v: f64§v_rest: f64§tau: f64§g_met: f64§x_half: f64§s_met: f64§ca: f64§tau_ca: f64§g_ca: f64§v_ca_half: f64§s_ca: f64§q: f64§c: f64§w: f64§m_pool: f64§y: f64§x_r: f64§k_rel: f64§l: f64§r_up: f64§k_d: f64§dt: f64

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impl InnerHairCell

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pub fn new() -> Self

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fn release_rate(&self) -> f64

Ca²⁺-dependent release function: Hill (n=2).

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pub fn step(&mut self, displacement: f64) -> f64

Step with stereocilia displacement (nm). Returns receptor potential (mV).

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pub fn reset(&mut self)

Trait Implementations§

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impl Clone for InnerHairCell

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fn clone(&self) -> InnerHairCell

Returns a duplicate of the value. Read more
1.0.0 (const: unstable) · Source§

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for InnerHairCell

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for InnerHairCell

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fn default() -> Self

Returns the “default value” for a type. Read more

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fn borrow_mut(&mut self) -> &mut T

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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
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