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NMDANeuron

sc_neurocore_engine::neurons::channels

Struct NMDANeuron 

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pub struct NMDANeuron {
Show 20 fields
    pub v: f64,
    pub h: f64,
    pub n: f64,
    pub s_nmda: f64,
    pub g_na: f64,
    pub g_k: f64,
    pub g_nmda: f64,
    pub g_l: f64,
    pub e_na: f64,
    pub e_k: f64,
    pub e_nmda: f64,
    pub e_l: f64,
    pub c_m: f64,
    pub phi: f64,
    pub mg_conc: f64,
    pub tau_rise: f64,
    pub tau_decay: f64,
    pub dt: f64,
    pub v_threshold: f64,
    pub gain: f64,

}
Expand description

NMDA receptor neuron — WB base + NMDA-type glutamate receptor current.

NMDA receptors require both glutamate binding (modelled as input current) AND membrane depolarisation (Mg2+ block removal) for activation. The Mg2+ block is voltage-dependent: at rest (-65 mV) channels are blocked, but depolarisation to -40 mV relieves ~80% of the block.

Key mechanism for:

  • Coincidence detection: requires presynaptic (glutamate) + postsynaptic (depolarisation) signals simultaneously
  • Synaptic plasticity: Ca2+ influx through NMDA triggers LTP/LTD
  • Working memory: NMDA-mediated recurrent excitation sustains persistent activity in prefrontal cortex
  • Slow synaptic integration: rise ~10 ms, decay ~100 ms

Jahr & Stevens, J Neurosci 10:1830, 1990; Wang, Neuron 22:409, 1999.

Fields§

§v: f64§h: f64§n: f64§s_nmda: f64§g_na: f64§g_k: f64§g_nmda: f64§g_l: f64§e_na: f64§e_k: f64§e_nmda: f64§e_l: f64§c_m: f64§phi: f64§mg_conc: f64§tau_rise: f64§tau_decay: f64§dt: f64§v_threshold: f64§gain: f64

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impl NMDANeuron

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pub fn new() -> Self

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pub fn step(&mut self, current: f64) -> i32

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pub fn reset(&mut self)

Trait Implementations§

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impl Clone for NMDANeuron

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fn clone(&self) -> NMDANeuron

Returns a duplicate of the value. Read more
1.0.0 (const: unstable) · Source§

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for NMDANeuron

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for NMDANeuron

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fn default() -> Self

Returns the “default value” for a type. Read more

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where T: ?Sized,

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fn borrow(&self) -> &T

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fn borrow_mut(&mut self) -> &mut T

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impl<T> CloneToUninit for T
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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
Performs copy-assignment from self to dest. Read more
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fn from(t: T) -> T

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fn into(self) -> U

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fn into_either(self, into_left: bool) -> Either<Self, Self>

Converts self into a Left variant of Either<Self, Self> if into_left is true. Converts self into a Right variant of Either<Self, Self> otherwise. Read more
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Converts self into a Left variant of Either<Self, Self> if into_left(&self) returns true. Converts self into a Right variant of Either<Self, Self> otherwise. Read more
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type Init = T

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